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Epidemiology of T2DM in childhood and associated disease complicationsInvestigating the incidence of childhood Type 2 Diabetes in the Western Australian community
Research
Intranasal Insulin Trial IIIf successful, this vaccine could prevent type 1 diabetes and the need for daily insulin injections in people at risk.
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The hidden burden of diabetesWhen Jodie and Brad Scott welcomed their fourth child Heath into the world, they were prepared for the many sleepless nights that come with caring for newborns.
Research
Women with type 1 diabetes exhibit a progressive increase in gut Saccharomyces cerevisiae in pregnancy associated with evidence of gut inflammationStudies of the gut microbiome have focused on its bacterial composition. We aimed to characterize the gut fungal microbiome (mycobiome) across pregnancy in women with and without type 1 diabetes.
Research
Continuous subcutaneous insulin infusion alters microRNA expression and glycaemic variability in children with type 1 diabetesTo determine whether continuous subcutaneous insulin infusion (CSII) vs. multiple daily injections (MDI) therapy from near-diagnosis of type 1 diabetes is associated with reduced glycaemic variability (GV) and altered microRNA (miRNAs) expression.
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Effects of dietary fat and protein on glucoregulatory hormones in adolescents and young adults with type 1 diabetesDietary fat and protein impact postprandial hyperglycaemia in people with type 1 diabetes, but the underlying mechanisms are poorly understood. Glucoregulatory hormones are also known to modulate gastric emptying and may contribute to this effect.
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Australasian Diabetes Data Network: Building a Collaborative ResourceA national collaboration was formed to provide longitudinal collection of T1D patient characteristics and outcomes, the Australasian Diabetes Data Network
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Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): Urinary screening and baseline biochemical and cardiovascular assessmentsIn adolescents with type 1 diabetes, the group with the highest tertile of albumin excretion showed more evidence of early renal and CV disease
Research
Renal and Cardiovascular Risk According to Tertiles of Urinary Albumin-to-Creatinine Ratio: The Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT)Urinary albumin-to-creatinine ratios at the higher end of the normal range at the age of 10-16 years is associated with an increased risk of progression to microalbuminuria
Research
ISPAD Clinical Practice Consensus Guidelines 2018: Assessment and management of hypoglycemia in children and adolescents with diabetesHypoglycemia is the commonest acute complication of type 1 diabetes