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Fetal androgen exposure and pragmatic language ability of girls in middle childhood

Prenatal exposure to testosterone has been shown to affect fetal brain maturation as well as postnatal cognition and behavior in animal studies.

Fetal androgen exposure and pragmatic language ability of girls in middle childhood:

This is the first prospective study to identify an association between early life testosterone exposure and pragmatic language difficulties in girls

Unpacking the complex nature of the autism epidemic

This paper discusses changes in diagnostic criteria, decreasing age at diagnosis, improved case ascertainment, diagnostic substitution, and social influences.

Adult psychosocial outcomes of children with specific language impairment, pragmatic language impairment and autism

Evidence that some children also develop autistic symptomatology over time has raised suggestions that developmental language disorder...

Cerebral dominance for language function in adults with specific language impairment or autism

A link between developmental language disorders and atypical cerebral lateralization has been postulated since the 1920s, but evidence has been indirect and...

Do children with autism 'switch off' to speech sounds? An investigation using event-related potentials

Autism is a disorder characterized by a core impairment in social behaviour. A prominent component of this social deficit is poor orienting to speech.

Autism and diagnostic substitution: Evidence from a study of adults with a history of developmental language disorder

Rates of diagnosis of autism have risen since 1980, raising the question of whether some children who previously had other diagnoses are now being diagnosed...

Evidence against poor semantic encoding in individuals with autism

This article tests the hypothesis that individuals with autism poorly encode verbal information to the semantic level of processing, instead paying greater...

Sertraline for anxiety in adults with a diagnosis of autism (STRATA): study protocol for a pragmatic, multicentre, double-blind, placebo-controlled randomised controlled trial

Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed to manage anxiety in adults with an autism diagnosis. However, their effectiveness and adverse effect profile in the autistic population are not well known. This trial aims to determine the effectiveness and cost-effectiveness of the SSRI sertraline in reducing symptoms of anxiety and improving quality of life in adults with a diagnosis of autism compared with placebo and to quantify any adverse effects. 

Autism likelihood in infants born to mothers with asthma is associated with blood inflammatory gene biomarkers in pregnancy

Mothers with asthma or atopy have a higher likelihood of having autistic children, with maternal immune activation in pregnancy implicated as a mechanism. This study aimed to determine, in a prospective cohort of mothers with asthma and their infants, whether inflammatory gene expression in pregnancy is associated with likelihood of future autism.