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Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models

This paper is a review of potential novel therapeutic targets or tools for the treatment of asthma and COPD.

Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infection

Asthma exacerbations are associated with human rhinovirus (HRV) infections, and more severe exacerbations are associated with HRV-C.

Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthma

These data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important...

Rhinovirus exacerbates house-dust-mite induced lung disease in adult mice

In this study, we combined human-rhinovirus infection with a clinically relevant mouse model of aero-allergen exposure using house-dust-mite in an attempt to...

Defective respiratory tract immune surveillance in asthma : A primary causal factor in disease onset and progression

The relative importance of respiratory viral infections vs inhalant allergy in asthma pathogenesis is the subject of ongoing debate.

ORIGINS Project shines light on Early Childhood Development

A collaboration between The Kids Research Institute Australia and Joondalup Health Campus is poised to be a game-changer for early childhood development.

WA researchers lead global centre to eliminate childhood asthma

An ambitious project that could stop children developing asthma is the centrepiece of a new world-class respiratory research centre launched in Perth.

Reducing the asthma burden: generous grant secured to develop world-first treatment

Researchers developing a world-first treatment that targets an underlying cause of asthma have secured a $499,640 grant from the Future Health, Research and Innovation Fund – Innovation Seed Fund.

The definition of asthma remission in children: A scoping review by the WAO Paediatric Asthma Committee

Asthma remission has emerged as a potential therapeutic goal. However, definitions of remission have primarily focused on adult populations, with limited consensus on how remission should be defined in children.