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A lifestyle intervention starting in the first-trimester pregnancy utilising e-health mode of delivery is feasible
We identified several novel candidate genes which warrant further analysis in cohorts matched more precisely for clinical phenotypes.
Overweight and obese children reported greater psychosocial distress than healthy weight children, and these differences were more pronounced for girls than boys.
IL8RA and IL8RB, encoded by CXCR1 and CXCR2, are receptors for interleukin (IL)-8 and other CXC chemokines involved in chemotaxis and activation of...
Australia’s biggest longitudinal study following the health and wellbeing of children from their conception through to childhood, has welcomed its 10,000th and final participant.
A researcher's work from 20 years ago has helped to crack one of biology’s biggest mysteries.
The rapidly developing coronavirus crisis is affecting our daily lives in unprecedented ways and brings with it uncertainty and fear.
Once upon a time it was infectious diseases like polio, measles or tuberculosis that most worried parents. With these threats now largely under control, parents face a new challenge – sky-rocketing rates of non-infectious diseases such as asthma, allergies and autism.
Research data from more than one million Australian and Welsh children will be examined to help better understand how the built environment affects child health and obesity, as part of an international research project to be co-led by The Kids Research Institute Australia.
Mapping murine genes controlling cutaneous leishmaniasis (CL) identified Fli1 as a candidate influencing resistance to L. major and enhanced wound healing.
Otitis media (OM) is among the most common illnesses of early childhood, characterised by the presence of inflammation in the middle ear cavity...
Genome wide linkage studies (GWLS) have provided evidence for loci controlling visceral leishmaniasis on Chromosomes 1p22, 6q27, 22q12 in Sudan...
ORIGINS Co-Director nominated in the 2024 Western Australian of the Year Awards
To identify new susceptibility loci for psoriasis, we undertook a genome-wide association study of 594,224 SNPs in 2,622 individuals with psoriasis...
The house dust mite allergen Der p 2 is one of the most important indoor allergens associated with allergic disease.
The Childhood Allergy and Immunology Research Team at The Kids Research Institute Australia are currently conducting four studies, through ORIGINS, investigating nutritional strategies in the diets of mothers and babies and how these may reduce the development of allergies.
A study of ORIGINS families has revealed a positive aspect to the COVID pandemic, with families found to benefit from the extra time together during lockdowns and mobile devices proving useful for helping them stay in touch with extended family and friends and for activities such as online classes.
Early onset Non-Communicable Diseases (NCDs), including obesity, allergies, and mental ill-health in childhood, present a serious and increasing threat to lifelong health and longevity. The ORIGINS Project (ORIGINS) addresses the urgent need for multidisciplinary efforts to understand the detrimental multisystem impacts of modern environments using well-curated large-scale longitudinal biological sample collections.
Desiree Dr Jackie Susan Lisa Zenobia Silva Davis Prescott Gibson Talati MBBS, FRACP, MPH, PhD BSc (Hons), PGradDipHlthProm, PhD MBBS BMedSci PhD