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Research

Immunogenicity and Immune Memory after a Pneumococcal Polysaccharide Vaccine Booster in a High-Risk Population Primed with Pneumococcal Conjugate Vaccine

PPV is immunogenic in 9-month-old children at high risk of pneumococcal infections and does not affect the capacity to produce protective immune responses

Research

Reproducibility of the plasma glucose response to moderate-intensity exercise in adolescents with Type 1 diabetes

The plasma glucose response to moderate-intensity exercise can be reproducible in adolescents with Type 1 diabetes

Research

Drug-gene modeling in pediatric T-cell acute lymphoblastic leukemia highlights importance of 6-mercaptopurine for outcome

This study advances our understanding of drug resistance in T-ALL and provides new markers for patient stratification.

Research

Heavy prenatal alcohol exposure and increased risk of stillbirth

The objective was to investigate the association between heavy prenatal alcohol exposure and stillbirth.

Research

Parental occupational exposure to engine exhausts and childhood brain tumors

Childhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown.

Research

Statistical adjustment of genotyping error in a case-control study of childhood leukaemia

Genotyping has become more cost-effective and less invasive with the use of buccal cell...

Research

Pre-pregnancy maternal overweight and obesity increase the risk for affective disorders in offspring

Maternal pre-pregnancy obesity has been linked with an increased risk for negative emotionality and inattentiveness in offspring in early childhood.

Research

The CDKL5 disorder is an independent clinical entity associated with early-onset encephalopathy

The clinical understanding of the CDKL5 disorder remains limited, with most information being derived from small patient groups seen at individual centres.

Research

Low-dose oral interferon alpha as prophylaxis against viral respiratory illness: A double-blind, parallel controlled trial

A double-blind, placebo-controlled clinical trial was conducted investigating the use of low-dose oral interferon alpha for preventing acute viral...

Research

Effect of early carriage of streptococcus pneumoniae on the development of pneumococcal protein-specific cellular immune responses in infancy

The aim of this study was to examine the relationship between nasopharyngeal pneumococcal colonization in early life and the development of T cell responses.