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Research

Lipoprotein lipase deficiency presenting with neonatal perianal abscesses

Evidence for potential deleterious effects of hypertriglyceridaemia on immune function, however, underlying mechanisms are poorly understood

Research

Distinguishing benign from pathologic TH2 immunity in atopic children

In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor

Research

Surgical fusion of early onset severe scoliosis increases survival in Rett syndrome: A cohort study

We investigated the impact of spinal fusion on survival and risk of severe lower respiratory tract infection in Rett syndrome.

Research

Improving access to primary care for Aboriginal babies in Western Australia: Study protocol for a randomized controlled trial

A population-based, stepped wedge, cluster randomized controlled trial of an enhanced model of early infant primary care

Research

A prospective cohort study assessing the reactogenicity of pertussis and influenza vaccines administered during pregnancy

Data on systemic and local reactions following receipt of TIV and dTpa during pregnancy support the safety of antenatal vaccination

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Seasonal trivalent influenza vaccination during pregnancy and the incidence of stillbirth: Population-based retrospective cohort study

Although antenatal influenza vaccination is an important public health intervention for preventing serious infection in pregnant women and newborns, reported...

Research

DeepCAGE transcriptomics identify HOXD10 as a transcription factor regulating lymphatic endothelial responses to VEGF-C

The role of HOXD10 in the regulation of VEGFR-3 signaling in lymphatic endothelial cells, and in the control of lymphangiogenesis and permeability

Research

Pressurised metered dose inhaler-spacer technique in young children improves with video instruction

Repeated video instruction over time improves inhaler technique in young children

Research

Soft neurological signs and prenatal alcohol exposure: A population-based study in remote Australia

Soft neurological signs were more common in children with prenatal alcohol exposure or FASD, consistent with the known neurotoxic effect of PAE

Research

ABCA3 lung disease in an ex 27 week preterm infant responsive to systemic glucocorticosteroids

This is a case of ABCA3 lung disease that demonstrated improvement after systemic glucocorticosteroid administration