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The last decade has seen rapid advances in the genetic technology that is allowing researchers to examine host-pathogen interactions at a whole organism level.
Congenital Toxoplasma gondii infection can result in intracranial calcification, hydrocephalus and retinochoroiditis. Acquired infection is commonly associated
To look at the interplay between PMN and macrophages in disease progression in humans we asked whether polymorphisms at genes that regulate their infiltration..
MMP1 is regulated by factors other than FLI1, and that the influence of IL-6 on MMP1 was independent of its effect on FLI1 in Leishmania braziliensis
Our results imply a role for IgG-mediated inflammation in determining delayed-type hypersensitivity associated with asymptomatic leishmaniasis
Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells.
These results highlight how UNICORN can enable reliable, powerful, and convenient genetic association analyses without access to the individual-level data
Findings from this study indicate that even in the absence of stroke, being at high polygenic risk of ischemic stroke is associated with lower cognitive ability
TNF mRNA expression was higher in leprosy patients compared to endemic controls, but did not differ significantly between clinical subgroups
We investigated the prevalence of UDT and examined rates of surgery and age at surgery in an Australian population.