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Immune cell trafficking from the brain maintains CNS immune toleranceEvaluation of fluorescently labeled leukocyte migration in mice revealed that DCs travel via the RMS from the CNS to the cervical LNs (CxLNs), where they...
Research
Reversible Control by Vitamin D of Granulocytes and Bacteria in the Lungs of Mice: An Ovalbumin-Induced Model of Allergic Airway DiseaseVitamin D may be essential for restricting the development and severity of allergic diseases and asthma, but a direct causal link between vitamin D...
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Exposure to UV Wavelengths in Sunlight Suppresses Immunity. To What Extent is UV-induced Vitamin D3 the Mediator Responsible?In experimental models, both vitamin D3-dependent and vitamin D3-independent pathways have been implicated in the mechanisms of UVR-induced systemic...
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UVR-induced immunosupressionDespite considerable advances, the exact mechanism whereby UVR can lead to changes in immune responses is not entirely clear at present, and no...
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Immune modulation by UV: Role of vitamin DIn this chapter, evidence for and evidence against the involvement of vitamin D in the immunoregulatory properties of UV radiation is presented.
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Optimized 25-hydroxyvitamin D analysis using liquid-liquid extraction with 2D separation with LC/MS/MS detection, provides superior precisionThe analysis of 25-hydroxyvitamin D3 (25(OH)D3) and related metabolites represents a considerable challenge for both clinical and research laboratories...
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The current state of play of rodent models to study the role of vitamin D in UV-induced immunomodulationUltraviolet radiation (UVR) from sunlight is immunomodulatory and the main source of vitamin D for humans.
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Maternal serum vitamin D levels during pregnancy and offspring neurocognitive developmentThe objective was to determine the association between maternal serum 25(OH)-vitamin D concentrations and behavioural, emotional and language outcomes...
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Vitamin D 3 deficiency enhances allergen-induced lymphocyte responses in a mouse model of allergic airway diseaseIn this study, using a mouse model, we determined whether vitamin D deficiency in utero and during early life modulated the severity of asthma.
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Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive DevelopmentNew research links poor language to lack of Vitamin D in womb.