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Hepatic iron loading in mice increases cholesterol biosynthesis

Iron and cholesterol are both essential metabolites in mammalian systems, and too much or too little of either can have serious clinical consequences

Prevalence of neural tube defects in Australia prior to mandatory

To establish baseline prevalence of neural tube defects (NTDs) prior to mandatory folic acid fortification in Australia.

Dietary glycaemic carbohydrate in relation to the metabolic syndrome in adolescents:

High dietary glycaemic carbohydrate, as measured by the dietary glycaemic index and glycaemic load has been associated with increased risk of the metabolic synd

Modern and traditional diets for Noongar infants

Breast- & bottle-feeding patterns & the introduction of solid feeds & sugar containing drinks to the dietary intake of a cohort of urban Aboriginal infants

Telethon donations fund early flu protection for bubs

Babies worldwide could have access to life-saving influenza vaccinations from just eight weeks of age thanks to researchers at The Kids Research Institute Australia and the generous support of the Telethon community.

Body mass index, adiposity rebound and early feeding in a longitudinal cohort (Raine Study)

This study examined the influence of type and duration of infant feeding on adiposity rebound and the tracking of body mass index (BMI) from birth to 14 years

Spinal pain and nutrition in adolescents-an exploratory cross-sectional study

Spinal pain is an important health issue for adolescents resulting in functional limitations for many and increasing the risk of spinal pain in adulthood.

Dietary intake and food sources of fatty acids in Australian adolescents

Dietary fat consumed during childhood and adolescence may be related to the development of cardiovascular and other chronic diseases in adulthood.

Exercise alone reduces insulin resistance in obese children independently of changes in body composition

The number of obese children with insulin resistance and type 2 diabetes is increasing, but the best management strategy is not clear.

Study suggests flu vaccine may take edge off RSV cases

A The Kids Research Institute Australia study has suggested the seasonal flu vaccine for children could also protect them from respiratory syncytial virus (RSV), with the dual benefit easing pressure on hospitals.

The role of family and maternal factors in childhood obesity

The aim of this study was to investigate the relationship between a child's weight and a broad range of family and maternal factors.

The STAMP RSV Program

STAMP RSV is a multifaceted program of work with the single focus to prepare the community for the uptake of new and emerging RSV immunisation strategies by providing the evidence to inform public health policy.

New partnership with Down Syndrome WA

Researchers from the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, are partnering with Down Syndrome WA to learn more about how respiratory syncytial virus, or RSV, affects children with increased medical vulnerability.

RSV Immunisation Guidance Tool

This tool is designed to help current and future parents and caregivers as well as health care providers. It is currently based on the 2026 Western Australian RSV immunisation program.

Researchers call for more oxygen machines in PNG to curb pneumonia deaths

A study by The Kids Research Institute emphasizes the need to measure oxygen levels in children with pneumonia, revealing that symptoms alone may miss critical hypoxia cases.

The Platform Trial In COVID-19 Priming and BOOsting (PICOBOO): The immunogenicity, reactogenicity, and safety of different COVID-19 vaccinations administered as a second booster

PICOBOO is a randomised, adaptive trial evaluating the immunogenicity, reactogenicity, and safety of COVID-19 booster strategies. We report data for second boosters among individuals 50-<70 years old primed with AZD1222 (50-<70y-AZD1222) until Day 84.

Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease

Acute lower respiratory tract infection (ALRI) remains a major worldwide cause of childhood mortality, compelling innovation in prevention and treatment. Children in Papua New Guinea (PNG) experience profound morbidity from ALRI caused by Streptococcus pneumoniae. As a result of evolutionary divergence, the human PNG population exhibits profound genetic variation and diversity. To address unmet health needs of children in PNG, we tested whether genetic variants increased ALRI morbidity. 

The Platform trial In COVID-19 vaccine priming and BOOsting (PICOBOO) booster vaccination substudy protocol

Coronavirus-2019 (COVID-19) vaccination in Australia commenced in February 2021. The first vaccines recommended for use were AZD1222 and BNT162b2, both delivered as a two-dose primary schedule. In the absence of sustained immunity following immunisation, recommendations for booster vaccination have followed. It is likely that periodic boosting will be necessary for at least some Australians, but it is unknown what the optimal booster vaccines and schedules are or for whom vaccination should be recommended. 

Childhood influenza vaccination rates improves with better access

More children across Australia are being vaccinated against the flu since funding was expanded and access widened under the National Immunisation Program